Dados do Trabalho

Título

ANALISYS OF PATIENTS WITH EPILEPSY IN THE CHILD NEUROLOGY OUTPATIENT CLINICAL OF AN UNIVERSITARY HOSPITAL

Introdução

The epilepsies comprise a broad group of disorders/diseases with diverse etiologies, diverse electroclinical presentations, and marked variability in clinical outcomes. The 2017 ILAE Classification of the Epilepsies defined three diagnostic levels including seizure type, epilepsy type, and epilepsy syndrome, emphasizing that etiology and comorbidities. Epilepsy syndromes have traditionally been grouped according to age at onset. The onset period of most cases occurs in childhood, highlighting the importance of studying the profile of this condition in the pediatric population.

Objetivo

This study aims to identify the epidemiological profile of children with epilepsy treated at a University Hospital.

Método

Analytical, observational and retrospective study. The medical records of 218 patients from the child neurology outpatient clinic were reviewed and the clinical information was entered into Excel. The inclusion criterion was a diagnosis of epilepsy. The data analyzed were based on age range of onset of seizures, gender, characterization of epileptic syndromes, type of seizures, etiology, treatment and history of febrile seizures and family history of epilepsy

Resultados

The age range at which the condition began was: 11.4% neonatal period, 51.4% infants, 18% preschool, 15% school, 0.9% adolescents. About gender, 60.4% male and 39.6% female. Regarding the type of crisis, 70.6% focal onset seizures, 21.5% generalized and 7.9% unknown. An epileptic syndrome was confirmed in 29.5%, among them: Infantile epileptic spasm syndrome 37.8%, Lennox-Gastaut syndrome 22.2%, Childhood Occipital Visual Epilepsy 4.4%, Self-limited Epilepsy with Centrotemporal Spikes 4.4%, Childhood Absence Epilepsy 2.8%, Early Infantile Developmental and Epileptic Encephalopathy 2.2%, Dravet Syndrome 2.2%, Epileptic Encephalopathy with Sleep-Activated Spike 2.2 %. As for treatment, 37% monotherapy and 63% polytherapy. Among the drugs, the main are valproic acid 21.7%, carbamazepine 20.5% and clobazam 17%. History of febrile seizure was observed in 14.9%.

Conclusão

The patient profile reveals a predominance of epilepsy onset in infants, a third associated with epileptic syndromes and Infantile Epileptic Spasms Syndrome being the most prevalent. Most patients treat polytherapy, with valproic acid being the most used antiepileptic drug. In this way, knowing the profile of the population served, it is possible to outline strategies for better care in a University Hospital.

Referências

Wireless, E; Tinuper, P; Perucca, E; Moshe, SL. Introduction to the Epilepsy syndrome Pampers. 2022.
Methodology for classification and definition of epilepsy syndromes with list of syndromes: Report of the ILAE Wireless, E; Nabbout, R; Scheffer, I.E, Tinuper, P; Balestrini, S; Wiebe, S; Perucca, E; Moshe, SL Task Force on Nosology and Definitions. 2022.

Palavras Chave

epilepsy; Epidemiology Epilepsy; Pediatric Epilepsy